Cytomegalovirus and Haritaki

Research indicates promising results for cytomegalovirus by using Haritaki

cytomegalovirus belongs to a family of viruses related to the herpes group. Researchers in Japan at the Department of Virology, Toyama Medical and Pharmaceutical University, studied the effect of haritaki on the cytomegalovirus in mice.

PMID: 8891165

Mice were subcutaneously treated with various doses of cyclosporine, and immunosuppression and MCMV infection were monitored by suppression of antibody production and virus yield in the lung, respectively.

Each herbal extract was orally administered to mice treated with 50 mg/kg of cyclosporine from a day before intraperitoneal infection, and the efficacy of herbs was evaluated by the reduction in the virus yield in the lung.
Terminalia chebula significantly suppressed MCMV yields in lungs of treated mice compared with water treatment.
Efficacy of oral treatment with 750 mg/kg per day of Geum japonicum extract was similar to that of the intraperitoneal administration of 2 mg/kg per day of ganciclovir in increasing the body weight of infected mice and reducing the virus yield in the lungs.
These herbs may be beneficial for the prophylaxis of CMV diseases in immunocompromised patients

How common is Cytomegalovirus (CMV)?

Between 50-80% of the population in the USA have Cytomegalovirus (CMV). However it does not complicate for most people. When it does interfere with health it shows up in various forms.

Symptoms and effects on the body can be very serious if the person has a weakened immune system already. Particularly at risk are HIV patients and people with autoimmune diseases.

Symptoms vary according to age and health of the patient. Some of the symptoms include:

  • Infants who are infected before birth usually show no symptoms of a CMV infection after they are born. They may develop severe symptoms including hearing loss, blindness, neurological, and developmental problems over time. Some infants may have other symptoms at birth including premature delivery, jaundice, enlarged liver and spleen, small head or microcephaly, being small for gestational age, seizures, rash, and feeding difficulties.

  • Newborns affected with the virus after birth by passing through the birth canal of an infected mother or by consuming breast milk from a mother with the virus or due to contact with an infected person usually show no symptoms of CMV infection. Some may develop pneumonia and other complications. If the babies have been born prematurely they are at a greater risk of complications.

  • Young children with the infection may develop insignificant illness. In some cases there may be complications like pneumonia, hepatitis, or a rash. Older children and healthy adults may have a few days or couple of weeks of mild illness with muscle pain, fatigue, headache, fever, and enlarged liver and spleen.

  • Those with a weakened immune system may develop severe complications like involvement of lungs, nervous system, gastrointestinal tract, and the eyes. source: 

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