Kabasura Kudineer benefits against Covid-19, Coronavirus Spike Protein

Kabasura Kudineer recommended in Tamil Nadu against COVID-19

kabasura kudineer is a herbal mixture recommended throughout South India as a treatment to prevent illness from virus, including the Coronavirus or COVID-19.

It has been known to the Siddha tradition of herbal medicine for thousands of years.

Kabasura kudineer is a Siddha medicine mixture of a number of different herbs, including clove, ginger, pippali, cirukancori roots, and many other herbs.

Here is a research report that details the findings of the research:

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247487/

Background

Siddha Medicine is a valuable therapeutic choice which is classically used for treating viral respiratory infections, this principle of medicine is proven to contain antiviral compounds.

Objective

The study is aimed to execute the In Silico computational studies of phytoconstituents of Siddha official formulation Kabasura Kudineer and novel herbal preparation – JACOM which are commonly used in treating viral fever and respiratory infectious diseases and could be affective against the ongoing pandemic novel corona virus disease SARS-CoV-2.

Method

Cresset Flare software was used for molecular docking studies against the spike protein SARS-CoV-2 (PDB ID: 6VSB). Further, we also conducted insilico prediction studies on the pharmacokinetics (ADME) properties and the safety profile in order to identify the best drug candidates by using online pkCSM and SwissADME web servers.

Results

Totally 37 compounds were screened, of these 9 compounds showed high binding affinity against SARS-CoV-2 spike protein. All the phytoconstituents were free from carcinogenic and tumorigenic properties. Based on these, we proposed the new formulation called as “SNACK–V”

Conclusion

Based on further experiments and clinical trials, these formulations could be used for effective treatment of COVID-19.

Kabasura Kudineer,Benefits against Covid-19 Coronavirus

Here is more detail on the research done on patients at different hospitals in the Tamil Nadu region of India:

Source: https://www.thehindu.com/sci-tech/health/siddha-research-papers-throw-light-on-efficacy-of-kabasura-kudineer-in-managing-covid-19/article31868238.ece

Incidentally, the Tamil Nadu government has also been promoting its consumption to boost immunity, although it has made it clear that it is not a medicine to treat COVID-19.

A study on two groups of COVID-19 positive cases both primary and secondary contacts, numbering 84 in nearby Vellore claim the study may be taken as a preliminary evidence of the protection offered by the herbal drink and its prophylactic effect in high risk COVID-19 cases.

The study by Dr. V. Vikramkumar, Assistant Medical Officer (Siddha), Tirupattur district, S. Ganesh, Director, Directorate of Indian Medicine and Homeopathy in Tamil Nadu, M.P. Sivanarul, Tirupattur District Collector, P. Parthiban, Joint Director, Directorate of Indian Medicine and Homeopathy, Tamil Nadu, and others was conducted in April.

It found that those who received kabasura kudineer intervention tested negative for COVID-19 on April 6, 2020 and those not administered the herbal concoction tested positive.

From the chisquare test analysis and graphical interpretation it emerged that there is an association between the intake of the concoction and the patients’ health status, according to the study.

Kabasura kudineer was distributed to 42 patients in quarantine facility at Agraharam in Tirupattur district.

At another facility in Jamiya College of Ambur taluk in the same district, Kabasura kudineer intervention was not resorted to for the subjects.

They were quarantined on April 1, 2020 and special attention was given to both groups.

No home-made food was given to them, but only that prepared and given by a supervision team.

For the treatment group, 60 ml of the concoction was administered daily after food to adults and 15 ml to children for 14 days.

Both groups comprised 42 patients each and their ages ranged between 3 and 70 years. All patients were quarantined on April 1, 2020.

A five-year-old male child in this group got relieved from dry cough after drinking four doses of kabasura kudineer under adult supervision.

Further, 10 patients got immediate relief from mild tiredness after the intake. No adverse effects were reported, according to the study.

Swabs for PCR for six cases (direct positive contact) on April 6 showed negative. Repeat sample tests on April 20 also showed negative results.

Secondary contacts tested on April 11, too, were negative. However they didnt develop any symptoms and no repeat tests were done.

In the control group all the cases were tested on April 6 and five primary contacts out of 42 tested positive and the others negative.

After 14 days quarantine period all others (secondary contacts) were out of symptoms and therefore no second testing was done for these cases.

Immediately after the COVID-19 pandemic was first reported from Wuhan, China, in December 2019, a team of Siddha doctors took up research on kabasura kudineer and Thonthasura Kudineer — the two Siddha formulations used against fevers due to respiratory infections.

Siddha medicine classifies disease and disorders into 4,448 types and has remedies for more than 64 types of fevers.

The detailed list of the contents of kabasura kudineer is as follows:

• Ingredients
  Ginger (Chukku)
• Piper longum (pippali)
• Clove (lavangam)
• Dusparsha (cirukancori ver)
• Akarakarabha
• Kokilaksha(mulli ver)
• Haritaki (kadukkaithol)
• Malabar nut (adathodai elai)
• Ajwain (Karpooravalli)
• Kusta (kostam)
• Guduchi (seenthil thandu)
• Bharangi (Siruthekku)
• Kalamegha (siruthekku)
• Raja pata (Vattathiruppi)
• Musta (korai kizhangu)
• Neer (Water)

Benefits of each herb in in kabasura kudineer

Source: https://www.netmeds.com/health-library/post/kabasura-kudineer-benefits-ingredients-and-side-effects-of-this-wonder-herbal-formulation

Benefits Of Ingredients:

This chooranam contains the following ingredients combined in equal proportions of 6.66% of each compound to make the formulation.

Ginger (Chukku) – It is known to promote digestion and is beneficial in treating asthma and other chronic respiratory ailments.

Piper longum (pippali) – It has the potential to treat indigestion, asthma and cough.

Clove (lavangam) – It has the power to kill the bacteria and promote liver health.

Dusparsha (cirukancori ver) – It is used to treat haemorrhoids.

Akarakarabha – It is used for healing mouth ulcers, sore throat, cough and ailments caused due to the worsening of vata dosha.

Kokilaksha(mulli ver) – A plant highly valued in ayurvedic medicine for treating jaundice, abdominal distention and urinary infections.

Haritaki (kadukkaithol) – Imbued with strong antioxidant and anti-inflammatory properties it facilitates to treat sore throat and allergies.

Malabar nut (adathodai elai) – It is used for treating upper respiratory infections and asthma.

Ajwain (Karpooravalli) – It helps in relieving common cold and cough.

Kusta (kostam) – A popular herb used in treating gout and respiratory ailment.

Guduchi (seenthil thandu) – It possesses antipyretic and immunomodulatory effects.

Bharangi (Siruthekku) – A strong herb used widely for treating allergic rhinitis, asthma and other inflammatory conditions.

Kalamegha (siruthekku) – It is used for cleansing and purifying the blood and liver.

Raja pata (Vattathiruppi) – A potent herb used for curing fever and intestinal worms.

Musta (korai kizhangu) – This herb eases fever and burning sensation.

How to make the drink from the powder of

kabasura kudineer:

This next video addresses the background of the Siddha medicine.

Government of India Official Covid Guidlines:

https://www.ayush.gov.in/docs/siddha-guidelines.pdf